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These transformations appear mainly in the liver, but also in the gastrointestinal tissue, lungs, kidneys, brain, and blood ( Furtado 2017) Several studies have shown that terpenes consumed orally are absorbed through the gastrointestinal tract and are bioavailable as soon as 0.5 h after intake, reaching their peaks between 2 and 4 h (Furtado 2017, Papada 2018)

In more recent years, non-daily smoking was also more common among those who vaped: this may partly reflect age differences between vapers and non-vapers (vaping prevalence has increased much more rapidly among younger than older adults in recent years [44,45,46])

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