We would need large, placebo-controlled trials with proper imaging and functional outcome measures to confirm these effects in humans
Should a patient become pregnant while using the solution, discontinuation is generally recommended until pregnancy and nursing have concluded
What the mechanism does NOT prove: Even if all the proposed mechanisms are real, they have been demonstrated primarily in animals or in vitro
While more human research is needed, current user feedback and practitioner insights suggest the following best practices: Standard Dosage Most users take 50100 mg per day , typically in divided doses (e.g., 2550 mg twice daily) to maintain stable blood levels
Strategies include testing isolated constituents versus the whole extract, using knockdown of specific pathways in cells or gene knockout models in animals to see if the effect persists, and applying pharmacological inhibitors to block suspected mechanisms