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Because of its psychotropic nature, marijuana use has been controversial due to potential health risks such as impaired learning and coordination, anxiety, and addiction

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published in Drug Testing and Analysis , 5.3% of 321 forensic drug test samples tested positive for HHC diastereomers, a figure that reflects both its growing use and its reliable detectability through conventional testing

and Spear, L.P., "Prenatal cocaine exposure increases the behavioral sensitivity of neonatal rat pups to ligands active at opiate receptors," Neurotoxicol