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Cell-culture (3T3-L1 adipocytes) 5-Amino-1MQ at 30 M strongly reduced 1-MNA levels in mouse fat cells, confirming NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

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According to studies on rodents, high levels of cytokines might be the cause of the characteristic symptoms of behaviour present in both development and adulthood in ASD (Depino, 2013)

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