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Some common challenges include: In a medical study, adults living with obesity, or with overweight and at least one weight-related medical problem, who took Wegovy pill, along with a reduced-calorie diet and increased physical activity, lost on average about 33 lb, which was about 14% of their starting body weight

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Randomized controlled trials have demonstrated that supplementation with B vitamins, including vitamin B 6 , effectively reduces blood concentrations of homocysteine