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1 In the US, smoking causes around half of all bladder cancers in both men and women, 2 making it the leading preventable risk factor, well ahead of workplace exposure to industrial chemicals

When consumed, nicotine enters the bloodstream and travels to the brain

Uncontrollable Tremors Uncontrollable tremors are physical spice withdrawal symptoms because the sympathetic nervous system becomes overactive as noradrenaline rebounds after being suppressed by 27 - 50% in the cerebral cortex, cerebellum, and hippocampus during active use [7]

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This flood of dopamine is unnatural and is what causes addiction