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In vitro studies often include compound stability analysis, redox response evaluation, and comparative testing under varied laboratory conditions
H., Bosque-Hamilton, P
Despite extensive research, most therapeutic candidates fail to achieve sufficient CNS exposure due to the restrictive bloodbrain barrier (BBB), which blocks over 98% of small molecules and nearly all biologics from entering the brain parenchyma
laboratory (HPLC with UV detection and mass spectrometry)
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