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Furthermore, genetic deletion/knockdown of FMO3 stimulated beiging of white adipose tissue and conferred protection against obesity in mice (Schugar et al., 2017)

For example, the U87-MG glioma that was found resistant to CR when grown as a subcutaneous xenograft in NOD-SCID mice 63 was responsive to CR when grown orthotopically in mice of a different genetic background

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[DOI] [PubMed] [Google Scholar] 16.Floh L

This method is often used in surgical planning and research