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46 In keeping with this, transgenic mice overexpressing GIP exhibit increased bone mass and enhanced osteoblast activity at 24 months of age, whilst GIPR KO leads to decreased BMD, cortical thickness, and overall bone strength

Measurement of reactive oxygen species Tenocytes were stained for reactive oxygen species (ROS) using the CellROX Deep Red Reagent (C10422, Thermo Fisher Scientific) for measuring ROS according to the manufacturers protocol

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