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It is typically prescribed for adults with obesity or those who are overweight with at least one weight-related condition like high blood pressure, type 2 diabetes, or high cholesterol

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A clinical study reported that the autophagy-mediated apoptosis caused by ROS production or ERK1/2 activation allows resveratrol to exert its antitumor effect on the apoptosis of human colon cancer cells through ROS-triggered autophagy 42

The deiodinases DIO1 and DIO2 can activate T4 by transforming it into T3 by removal of the 5-iodine, while DIO1 and DIO3 can prevent T4 from being activated by converting it to the inactive reverse T3 ( Reference Darras and Van Herck 68 ) (Fig