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They overlap only at the GLP-1 receptor and add different second pathways, so they are not the same class and not interchangeable

Recommendation Use for 46 weeks Then take a 24 week break This break allows NNMT levels to rebound and resensitizes the body to the peptides metabolic signaling

B12 injections skip the digestive system as they enter the bloodstream directly

Splitting vials across titration phases Some researchers reconstitute their 10 mg vial at a higher concentration (5 mg/mL with 2 mL water) for the later phases when precision is less critical and injection volume matters more

The protocol is technically still running, the response is not