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We used an mGIPR-Ab that fully neutralizes GIPR activity in vitro and prevents body weight gain in obese mice when dosed systemically 17

Weisberg SP, Hunter D, Huber R, Lemieux J, Slaymaker S, Vaddi K, et al

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However, further studies are still needed to optimize its clinical application, including dosage form improvement, combination therapy strategies and long-term safety assessment

The regulatory gaps that exist for research chemicals place full responsibility for safety and quality on the individual - a significant burden that should be approached with realistic expectations about the current state of evidence