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This could mean starting with a lower dose, taking more time to increase the dose, or using a lower maintenance dose

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[DOI] [PMC free article] [PubMed] [Google Scholar] 207.Trickett KH, Matiaco PM, Jones K, Howlett B, Early KB

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In addition, residues N338 to T343 in the intracellular loop 3 (ICL3) of the compound 2GLP-1GLP-1RG s and compound 2LY3502970GLP-1RG s complexes, F369 to R376 in the extracellular loop 3 (ECL3) of the compound 2GLP-1RG s and compound 2LY3502970GLP-1RG s complexes, and P56 to F61 in the ECD of the compound 2GLP-1RG s complex were also poorly resolved and thus omitted from the corresponding final model