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Ballard and colleagues (Growth Regulation, 1993) reported that IGF-I binds IGFBP-3 with roughly one thousand times the affinity of LR3IGF-I, and Wilson and colleagues (2000) found that, unlike IGF-I, the Long R3 variant did not raise serum IGFBP-3 in adolescent monkeys

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The costs of medicines to treat patients with diabetes, coupled with the cost of associated complications, have increased the economic burden of diabetes in the region

Your healthcare provider may recommend several approaches, including dose adjustment (temporarily reducing or pausing Wegovy), additional monitoring with more frequent follow-up appointments, referral to mental health services for specialist assessment and support, or discontinuation of treatment if the risks outweigh the benefits in your individual circumstances