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Acute kidney injury (AKI) causes approximately two million deaths each year worldwide [18,19] among patients with generalized or localized renal ischemic injury due to surgery, sepsis or trauma, and toxic responses to medication (often in combination) [20,21,22]

[15] [16] Tests may include full blood count, serum B12 levels, anti-intrinsic factor antibodies (to diagnose pernicious anaemia), and sometimes methylmalonic acid or homocysteine levels when the diagnosis is uncertain

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10.3389/fimmu.2022.832394 [DOI] [PMC free article] [PubMed] [Google Scholar] 335.Labarrere CA, Kassab GS