If you dig into the research, we've got decades worth
doi:10.1002/14651858.CD004426.pub3
The compound is described in the literature as pleiotropic: its downstream effects engage multiple biological systems simultaneously, and its primary binding receptor has not yet been identified
[DOI] [PubMed] [Google Scholar] 26.Nicze M., Dec A., Borwka M., Krzyak D., Bodys A., Budak ., Okopie B
Some people taking GLP-1 medications may experience digestive side effects, with these being the most common: Nausea, especially at the start or after a dose increase Heartburn or stomach discomfort after meals Constipation, which can occur as the body adjusts Diarrhea, which may be mild or bothersome Vomiting, sometimes along with nausea Most digestive side effects lessen as the body adjusts