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Antioxidants (basel)

By modulating TRP availability, central KP flux, glutamatergic signalling, oxidative stress, HPA-axis activity, and neuroplasticity, the microbiome-immune-BBB axis emerges as a mechanistic bridge linking peripheral physiology to central mood regulation

[DOI] [PMC free article] [PubMed] [Google Scholar] 140.Brown V.A., Patel K.R., Viskaduraki M., Crowell J.A., Perloff M., Booth T.D., Vasilinin G., Sen A., Schinas A.M., Piccirilli G., et al

No clinical use is implied

Its primary function is to disrupt the interaction between FOXO4 and the tumor suppressor protein p53, leading to the selective apoptosis of senescent cells and a deceleration of biological aging