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Dysbiosis, or an imbalance in the gut microbiome, has been associated with increased systemic inflammation and exacerbated BBB dysfunction in a variety of conditions, including I/R injury (Kaur et al., 2023)

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Therefore, these susceptible organisms have intrinsic mechanisms to protect from oxidative damage

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Brogi S et al (2014) Disease-modifying anti-Alzheimers drugs: inhibitors of human cholinesterases interfering with beta-amyloid aggregation