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Contribution of Pyk2 pathway and reactive oxygen species (ROS) to the anti-cancer effects of eicosapentaenoic acid (EPA) in PC3 prostate cancer cells

Even though intravascular hemolysis in persons with AHA that is associated with G6PD deficiency is important in pathophysiology and diagnosis, a substantial proportion of the hemolysis is extravascular (as shown by the enlarged spleen)

An exemplary batch of gel formulation containing, for example, 1.5% of a JNK inhibitor described herein is prepared by dissolving Poloxamer 407 (BASF Corp.) in 50 mM Tris buffer and 77 mM NaCl solution with a pH between 5.5-8.0

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