Starting with high doses (1,000 mcg to 2,000 mcg) weekly or biweekly is common
Efficacy of GLP-1 Receptor Agonists in Breast Cancer Populations Sherry Shen, MD Sherry Shen, MD, broke down early data from MSK evaluating the role GLP-1s play in survival and helping to manage long-term outcomes in breast cancer
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Because of this, semaglutide should not be used in people with: A personal or family history of medullary thyroid carcinoma (MTC) MEN2 (Multiple Endocrine Neoplasia syndrome type 2) Other serious risks that have been reported with GLP-1 receptor agonists include pancreatitis, gallbladder disease, potential kidney problems, and (in some regulatory guidance) the need to monitor for changes in mood or suicidal thoughts
Its important to remember that the 0.84 hazard ratio observed with tirzepatide in other words, the 16% relative benefit was not against placebo but against a very good drug that had already shown cardiovascular benefits, Dr