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559 Recent studies show that PPAR stimulation leads to hepatocyte hypertrophy in the pericentral region and increased proliferation in the periportal region, promoting liver repair in a YAP/TEAD-dependent manner after PHx

Nationwide prevalence and characteristics of transthyretin amyloid cardiomyopathy in Sweden

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Reported applications include radioligand and fluorescent binding assays at CTR and AMY1 to AMY3, cAMP accumulation and other Gs-pathway readouts, receptor internalisation and regulation studies, and structural biology: Cao and colleagues (Nat Commun, 2025) reported cryo-EM structures of cagrilintide bound to calcitonin and amylin receptors with associated PDB depositions