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This member of the G protein-coupled receptor family, located on the cell membranes of various tissues, plays a key role in regulating glucolipid metabolism, insulin secretion, and cardiocerebrovascular protection within the body

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It is well known that activation of efferent renal nerves exhibits the anti-diuretic effect by increased renin secretion, sodium reabsorption and renal vascular resistance [37, 38]