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The three-amino-acid truncation transforms IGF-1 from a highly regulated, IGFBP-bound mediator into a potent, locally-acting growth factor with minimal systemic distribution

One of the primary metabolites of BPC-157 is thought to be Proline, which has been shown to play a role in superoxide production and intracellular cascades whose downstream effects could interfere with a variety of biomolecules leading to widespread pathologic effects [23, 51, 74, 75]

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Then, nodule staining was destained by 10% cetylpyridinium chloride (CPC) in 10 mM sodium phosphate for 30 minutes at room temperature