Gulke, E., Gelderblom, M
free radical scavenging activity, suppression of intracellular calcium influx, blockage of Na + channel activation, reduction of intracranial pressure, tissue edema, and inflammation (Santos et al., 2003)
H., Lee, M
Consider initial therapy at this stage when blood glucose 300 to 350 mg/dL (16.7 to 19.4 mmol/L) and/or HbA1C 10%-12% (86 to 108 mmol/mol), especially if the patient is symptomatic or if catabolic features (eg, weight loss, ketosis) are present, in which case basal insulin + mealtime insulin is the preferred initial regimen
For each case profile, we randomly sampled 1 patient visit from the subset of test set IV visits that match the profile, while ensuring diversity and representation across secondary criteria covering (a) drug classes in active prescription, (b) number of comorbidities and (c) types of comorbidities