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Glutamine and Autophagy in Cancer Research Glutamine plays a significant role in autophagy, a process where cells break down their own components for nutrients: Promoting Cancer Survival : When nutrients run low, glutamine supports autophagy, allowing cancer cells to sustain themselves

Moreover, the impact of environmental factors can differ depending on an individuals genetic background

Its structure can therefore be written as H-Ala-Glu-Asp-Gly-OH

Studies have shown that ACSL4-enriched exosomes can be phagocytosed by microglia, leading to the activation of the nuclear factor kappa-B (NF-B) signaling pathway and polarization of microglia toward a proinflammatory M1 phenotype, thereby amplifying neuroinflammation (He et al., 2024)