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In addition, oxidative DNA damage can interfere with gene transcription and effect promoter function, resulting in transcription damage and mutation of key genes

DISCUSSION Oxidative stress is a major pathogenetic event occurring in several liver disorders ranging from metabolic to proliferate ones, and is a major cause of liver damage in Ischemia/Reperfusion during liver transplantation

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Am J Physiol Endocrinol Metab 300:E1038E1046

Morphological and structural attributes were identified and recorded previously by transmission electron microscopy (TEM) (Singh et al., 2018)