Our prior work in this TTS noise-exposure model demonstrated that ribbon synapse loss across these tonotopic frequency regions is both rapid (i.e
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No significant differences were noted in the secondary outcomes post-weighting between these two groups, with all results consistent across multiple sensitivity analyses
The presynaptic ribbons (red channel) were identified through segmentation, then quantified and tracked in the z-dimension to avoid superimposition ambiguity or overestimation in each stack
11 Furthermore, hyperglycemia itself, resulting from insulin resistance, induces a pro-inflammatory environment through its effect on immune cells
