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Patients should monitor for signs of hypoglycemia, especially if taking other glucose-lowering medications, and have a plan in place to quickly correct low blood sugar when needed (such as consuming glucose tablets or a fast-acting carbohydrate)

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How long you feel the effects can depend on your starting levels, which is why people with a larger deficiency sometimes notice the benefits over a longer stretch

Tirzepatide trials (SURPASS 14) show comparable patterns: initial variability followed by net improvement in most patients, particularly those achieving sustained weight loss

You don't need diabetes, or any diagnosis, to qualify, and most of our patients don't have it