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Vitamin B12 is an essential, water-soluble vitamin

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Significant reduction in all-cause mortality with Ozempic 1 For adults with T2D and CKD for a confirmatory secondary endpoint: time to first occurrence of all-cause mortality vs placebo when both were added to standard of care 1,2 All cause death 1-3 1-3 cc 2.5% ARR reported at 3 years in pre-specified supplementary analysis

The combination with niacinamide lacks clinical validation for its safety, stability, or long-term effectiveness