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The therapeutic effects of probiotics are multifactorial and exhibit substantial interindividual variability, influenced by the composition and metabolic activity of the hosts resident gut microbiota, the specific probiotic strain or strain combination employed, and the precise site of action within the GI tract (143)

396,397,398,399 GLP-1RAs and nerve cells GLP-1 can modulate peripheral nerves through the ERK (extracellular signal-regulated kinase) signaling pathway, reducing the occurrence of neurological dysfunction

PMC Turro et al

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In a ventilation-induced lung injury (VILI) model, pretreatment with CMT-3 decreased neutrophil infiltration and myeloperoxidase levels, which correlated significantly with MMP-9 activity