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Notably, a recent clinical study evaluating TM combined with anti-PD-1 therapy in patients with locally advanced OSCC reported an objective response rate (ORR) of 57.8% and a 12-month overall survival (OS) rate of 80.0%, highlighting its potential to overcome immunotherapy resistance (225)

So if youre looking for a medication that can help you lose weight, Metformin may be worth considering, but its important to note that, on average, 60% of those who take Metformin report weight loss