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Therefore, compared to healthy individuals of the same altitude and ethnicity, the increased abundance of Verrucomicrobia and Akkermansia may offer significant benefits to hypertensive patients in adapting to high-altitude environments by regulating energy metabolism and modulating inflammatory responses

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In view of the demographics of the world population in between 2000 and 2050, the population over 60 years is expected to grow from 605 million to 2 billion people (World Health Organization, 2014)

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