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The present study demonstrated that NNMT inhibitor administered during adipocyte differentiation blocked the accumulation of lipid droplets, suggesting suppressed lipogenesis and programed development of mature adipocytes from pre-adipocyte 3T3-L1 precursor cells (i.e., adipogenesis)

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The compound inhibits the NNMT enzyme in fat cells, which increases cellular NAD+ levels and shifts adipocyte metabolism from fat storage to fat burning

Among these, 5 Amino 1mq has truly captured the attention of the scientific community

By the mid-2010s, 5-Amino-1MQ emerged as one of the compounds used in experimental NNMT-related research investigating metabolic signalling and enzyme regulation