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Diagnosis of prediabetes

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If you think of all the possible mechanisms, across GLP-1, GIP, amylin, and even cannabinoid receptors, you get a giant Venn diagram of overlapping options

Also, the combination of GLP-1 agonists with SGLT-2 inhibitors and novel insulin sensitizers are under investigation as a triple combination therapy for patients with diabetes resistant to various current dual therapy regimens, and initial trials are encouraging in reaching glycemic goals in patients who have failed to respond to traditional dual therapy interventions

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