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l-ornithine and L-aspartate l-Ornithine and L-aspartate (LOLA) are substrates for the urea cycle and can increase urea production in periportal hepatocytes

R For patients with GST null genotypes, aggressive support of glutathione status ( NAC , liposomal glutathione , sulforaphane for NRF2 induction of remaining GST isoforms) is essential

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