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It is also important to note that early-phase trials such as those conducted for retatrutide typically exclude participants with active major depressive disorder or suicidal ideation, which may limit the detection of psychiatric adverse events in the published data

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There have been some side effects reported in people who take excessive taurine, like vomiting, nausea, liver pain, headache and stomach pain, Zumpano says

Patent expirations, generics competition, and a global surge in metabolic drug development could dramatically increase the number of trials targeting obesity and metabolic disease