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TB-4: Clinical Data for Unrelated Endpoints Meaningful human trial data for full-length TB-4 (corneal-healing Phase 2/3 as RGN-259, plus cardiac and wound-repair programs) Clean Phase 1 safety Cosmetic dosing is extrapolated from these programs Note: Full-length trial data does not transfer to the TB-500 fragment, so verify vial identity

These receptor complexes are found in several key locations throughout the body, including the brain, stomach, and kidney

Mechanism of Action: Research suggests it promotes angiogenesis (new blood vessel formation), collagen synthesis, and cellular signaling pathways that accelerate recovery

Restore lost volume in the cheek above (this is the source of the extra loose skin that creates jowls - not skin laxity - for the most part) - this is usually done with dermal fillers 2

AOD-9604 Supplies Needed Plan based on subcutaneous research dosing of 300-500 mcg/day from a 5 mg vial reconstituted with 3.0 mL bacteriostatic water