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Source : PATH study public-use files for adults from waves 1 to 3

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At the same time, the FDA is focused on cracking down on e-cigarette use

Antidepressant actions via monoamine oxidase inhibition (from unknown components from cigarettes) and nicotine-derived compensation effects of psychiatric medications also rationalize the phenomenon of more smokers among psychiatric patients compared with healthy adults 13

The key question is whether this is expected short-term sedation, a dose problem, a timing problem, a sign that depression is still active, or an interaction with another medication or substance