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References Beighton P, De Paepe A, Steinmann B, Tsipouras P, Wenstrup RJ

Biochemical evidence indicated that energy failure due to defects in oxidative phosphorylation altered vascular tone and prevented the recycling of reactive oxygen species, which are possible mechanisms responsible for triggering migraine headaches (141)

Paraptosis can be induced by various triggers, such as activating the insulin-like growth factor 1 receptor (IGF1R), proteasomal inhibition leading to ER stress, ROS generation, and calcium influx into mitochondria

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L-Carnitine and Acetyl-L-Carnitine alone have been shown to support improved count, concentration, motility and morphology, as well as to protect sperm, which are particularly susceptible to free radical damage.* "Approximately, 30-80% of infertility cases are caused by oxidative stress and decreased level of seminal total antioxident capacity." In addition to Carnitine, Total Fertility Advantage for Men includes potent antioxidents and essential trace elements like Coenzyme Q10, Zinc, Vitamin C, N-Acetyl Cysteine (NAC), Lycopene, and Selenium for optimal reproductive health.* Total Fertility Advantage for Men contains 400mcg of Folate which has been shown to improve sperm concentration, and when combined with Zinc, also shows improvement in sperm morphology.*